BDB553723
CD40 Hamster anti-Mouse, FITC, Clone: HM40-3, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB553723-Each-of-1 | In Stock | ₹ 33,108.00 |
BDB553723 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,108.00
GST (18%): ₹ 5,959.44
Total Price: ₹ 39,067.44
Antigen
CD40
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Immunogen
(BALB/c x NZB)F1 mouse-derived lymphoma WEHI-231
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Mouse, Rat
Isotype
IgM κ
Applications
Flow Cytometry
Clone
HM40-3
Conjugate
FITC
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The HM40-3 antibody reacts with CD40, a 40-50-kDa glycoprotein expressed on B lymphocytes and other antigen-presenting cells
- The CD40 molecule has a central role in B-cell growth and differentiation
- Furthermore, interactions of CD40 with its ligand, CD154, are involved in the initiation and effector stages of cell-mediated immune responses
- CD40 may be involved in the triggering of NK cells and NK-T cells
- Soluble HM40-3 antibody stimulates splenic and peritoneal B cells to proliferate in vitro
- This antibody also induces spleen B cells to express the costimulatory molecules CD80 (B7-1) and CD86 (B7-2)
- HM40-3 mAb has been demonstrated to inhibit the binding of soluble CD154 (gp39, CD40 Ligand) to soluble CD40 and to cell-surface CD40
- This hamster mAb to a mouse leukocyte antigen has been observed to cross-react with similar populations of Lewis, Sprague-Dawley, and LOU16 rat leukocytes.