BDB554228
p21 Mouse anti-Human, Unlabeled, Clone: 6B6, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB554228-Each-of-1 | In Stock | ₹ 32,040.00 |
BDB554228 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,040.00
GST (18%): ₹ 5,767.20
Total Price: ₹ 37,807.20
Antigen
p21
Classification
Monoclonal
Concentration
0.5mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Human p21
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Human
Isotype
IgG1
Applications
Western Blot
Clone
6B6
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- Description p21 belongs to a class of tumor suppressors including p16 and p27 which control progression through the cell cycle by inhibiting the activity of cyclin-cdk complexes
- p21 is also known as senescent cell-derived inhibitor 1 (Sdi1), wild-type p53-activated fragment 1 (Waf1), Cdk-interacting protein 1 (Cip1), p21 and p53-regulated inhibitor of Cdks (Pic1)
- p21 mRNA is expressed at higher levels in senescent fibroblasts than in actively growing cells
- When introduced into proliferating foreskin fibroblasts, p21 inhibits DNA synthesis and cell cycle arrest
- p53 can activate p21 gene expression via a p53 binding site identified in the promoter of the p21 gene
- Host Species: Mouse Clone: 6B6 Isotype: IgG1 Species Reactivity: Human Immunogen: Human p21 Formula Weight [Chemical]: 21kDa Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting