BDB554829

CD3 Mouse anti-Rat, NA/LE, Unlabeled, Clone: G4.18, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554829-Each-of-1 In Stock ₹ 39,694.00

BDB554829 - Each of 1

₹ 39,694.00

In Stock

Quantity

1

Base Price: ₹ 39,694.00

GST (18%): ₹ 7,144.92

Total Price: ₹ 46,838.92

Antigen

CD3

Classification

Monoclonal

Concentration

1.0mg/mL

Formulation

No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen

PHA-stimulated rat lymph node and spleen cells

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Rat

Isotype

IgG3 κ

Applications

Flow Cytometry

Clone

G4.18

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • Description The G4.18 antibody reacts with the T-cell receptor-associated CD3 cell-surface antigen found on thymocytes, peripheral T lymphocytes, and dendritic epidermal T cells
  • It has been reported that CD3 expression is down-regulated within 24 hours in concanavalin A-stimulated rat T cells, and soluble mAb inhibits the allogeneic mixed-lymphocyte proliferative response and cell-mediated cytotoxicity to allogeneic target cells
  • In vivo treatment with G4.18 mAb prevents cardiac and skin allograft rejection, resulting in donor-specific tolerance
  • Pre-incubation of splenocytes with the alternate anti-rat CD3 monoclonal antibody, 1F4 blocks staining with mAb G4.18.