BDB555070
CD123 Rat anti-Mouse, Biotin, Clone: 5B11, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB555070-Each-of-1 | In Stock | ₹ 39,516.00 |
BDB555070 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,516.00
GST (18%): ₹ 7,112.88
Total Price: ₹ 46,628.88
Antigen
CD123
Classification
Monoclonal
Concentration
0.5mg/mL
Description
Il3ra; IL-3RA; IL-3R-alpha; IL-3 Receptor alpha; IL-3 Receptor α; SUT-1
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
5B11
Conjugate
Biotin
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse IL-3R transfected CTLL cells
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a κ
Related Products
Description
- The 5B11 monoclonal antibody specifically recognizes mouse CD123, the α chain subunit (IL-3R α ) of the mouse IL-3 receptor
- The IL-3R α chain is a 60-70 kD transmembrane glycoprotein that binds IL-3 with low affinity but cannot transduce signals by itself
- The mouse IL-3R α chain can complex with either of two homologous β chain subunits ( β c and β α subunits of the mouse IL-3R, IL-5R and GM-CSFR to form high-affinity receptors
- The β IL-3 subunit can form high affinity IL-3 receptor complexes with only the IL-3R α subunit
- The β IL-3 subunit clone is specific for mouse IL-3 and binds with low affinity
- The immunogen used to generate the 5B11 hybridoma was CTLL cells transfected with the mouse IL-3R alpha chain
- The 5B11 antibody does not block the binding of IL-3 protein to the high affinity IL-3 receptor heterodimer.