BDB558036

c-Jun (pS63) Mouse, Unlabeled, Clone: 2/C-JUN (PS63), BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558036-Each-of-1 In Stock ₹ 49,484.00

BDB558036 - Each of 1

₹ 49,484.00

In Stock

Quantity

1

Base Price: ₹ 49,484.00

GST (18%): ₹ 8,907.12

Total Price: ₹ 58,391.12

Antigen

c-Jun (pS63)

Classification

Monoclonal

Concentration

0.25mg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Phosphorylated Human c-Jun

Quantity

0.1 mg

Research Discipline

Cell Biology

Target Species

Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

2/C-JUN (PS63)

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • The activator protein transcription factor (AP-1) was identified as a protein that recognizes specific sequences in the cis-control regions of the SV40 virus and the human metallothionein IIA gene
  • AP-1 is composed of protein products of two different gene families: jun and fos
  • The AP-1 transcription factor is either a homodimer of Jun proteins or a heterodimer of Jun and Fos proteins
  • The transcriptional activity of Jun is enhanced by phosphorylation of serines 63 (S63) and 73 in its activation domain
  • Phosphorylation at both sites is necessary for stimulating the activating function of Jun
  • Jun is phosphorylated by JNK protein kinases that are activated by the same signals that potentiate Jun activity
  • The 2/c-Jun/(S63) monoclonal antibody recognizes the phosphorylated S63 of c-Jun
  • Host Species: Mouse Clone: 2 Isotype: IgG1 Species Reactivity: Human Immunohistochemistry (Formalin-Antigen Retrieval Required), Western Blotting