BDB559369
CD34 Mouse anti-Canine, PE, Clone: 1H6, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB559369-Each-of-1 | In Stock | ₹ 23,852.00 |
BDB559369 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,852.00
GST (18%): ₹ 4,293.36
Total Price: ₹ 28,145.36
Antigen
CD34
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Dog CD34-IgG2a fusion protein and dog myelomonocytic leukemia ML3
Quantity
0.1 mg
Research Discipline
Cell Biology
Target Species
Canine
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
1H6
Conjugate
PE
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 1H6 antibody reacts with CD34, an ∽110 kDa glycoprotein on the surface of bone marrow-derived progenitors of hematopoietic and endothelial cells
- In the bone marrow, 1-3% of cells are stained with 1H6 mAb; whereas peripheral blood leukocytes are not stained
- Immunomagnetic depletion of lineage-committed leukocytes from bone marrow results in about three-fold enrichment of CD34+ cells
- CD34+ hematopoietic progenitors may be mobilized to the peripheral blood by treatment with recombinant canine granulocyte colony-stimulating factor and stem-cell factor
- Furthermore, CD34 is expressed on some canine leukemias
- In the mouse, CD34 is also expressed on high endothelial venules (HEV) of lymph nodes and, in this form, functions as a ligand for L-selectin
- CD34 expression on HEV of dog lymph nodes has been demonstrated with polyclonal anti-CD34 antibody.