BDB560106

CD172a Rat anti-Mouse, APC, Clone: P84, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB560106-Each-of-1 In Stock ₹ 38,092.00

BDB560106 - Each of 1

₹ 38,092.00

In Stock

Quantity

1

Base Price: ₹ 38,092.00

GST (18%): ₹ 6,856.56

Total Price: ₹ 44,948.56

Antigen

CD172a

Classification

Monoclonal

Concentration

0.2mg/mL

Description

SIRPα, SHPS-1, BIT

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

P84

Conjugate

APC

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Membrane fractions from mouse brain

Quantity

0.1 mg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The P84 antibody reacts with CD172a, also known as SIgnal-Regulatory Protein α (SIRPα), Src Homology 2 domain-containing protein tyrosine Phosphatase (SHP) Substrate 1 (SHPS-1), or Brain Immunoglobulin-like molecule with Tyrosine-based activation motifs (BIT)
  • CD172a is an adhesion molecule of the Ig superfamily which is expressed on neurons in the central nervous system and the retina, on macrophages, and on bone-marrow myeloid cells
  • Its ligand, CD47, or Integrin-Associated Protein (IAP), is expressed by a wide variety of cells
  • CD172a and CD47 are proposed to mediate bi-directional signaling to modify neural synaptic activity and regulate the phagocytic activities of macrophages.