BDB559519

CD81 Hamster anti-Mouse/Rat, PE, Clone: EAT2, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB559519-Each-of-1 In Stock ₹ 23,318.00

BDB559519 - Each of 1

₹ 23,318.00

In Stock

Quantity

1

Base Price: ₹ 23,318.00

GST (18%): ₹ 4,197.24

Total Price: ₹ 27,515.24

Antigen

CD81

Classification

Monoclonal

Concentration

0.2mg/mL

Description

TAPA-1; Tspan28; Tapa1; Tapa-1; Target of the antiproliferative antibody 1;

Host Species

Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

EAT2

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

CD81+ mouse B lymphoma 38C13

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse, Rat

Isotype

IgG1 κ

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Description

  • Description The Eat2 antibody reacts with CD81, a 26kDa nonglycosylated member of the transmembrane 4 integral membrane protein superfamily, expressed by many types of cells
  • For example, CD81 participates with CD19 and CD21 in the signal transduction complex associated with the B-cell receptor on human B lymphocytes and with the CD4 and CD8 co-receptors on human thymocytes and T lymphocytes
  • In mouse fetal thymic organ culture, interactions of immature thymocytes with CD81 expressed by thymic stromal cells are required to induce development of T cells with αβ T-cell receptors
  • Furthermore, CD81 has been shown to play a role in the regulation of rat mastcell degranulation
  • Despite its important roles in the immune response and wide tissue distribution, CD81-deficient mice are born without obvious developmental abnormalities
  • However, these mice have abnormal immune responses, and impaired fertility
  • Eat2 mAb cross-reacts with the rat CD81 antigen
  • Eat2 mAb was reported cross-reacting with the rat CD81 antigen
  • Flow Cytometry