BDB562483
IL-2 Rat anti-Mouse, PE-CF594, Clone: JES6-5H4, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562483-Each-of-1 | In Stock | ₹ 20,826.00 |
BDB562483 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 20,826.00
GST (18%): ₹ 3,748.68
Total Price: ₹ 24,574.68
Antigen
IL-2
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Il2; Interleukin-2; T-cell growth factor; TCGF
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2b
Applications
Flow Cytometry
Clone
JES6-5H4
Conjugate
PE-CF594
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen
Mouse IL-2 Recombinant Protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- Description The JES6-5H4 monoclonal antibody specifically binds to mouse interleukin-2 (IL-2)
- IL-2 is a multifunctional cytokine that plays pivotal roles in immunity and tolerance
- It is produced by activated T cells
- IL-2 effects the activation, growth, proliferation and/or differentiation of various cell types including T and B lymphocytes and their precursors, LAK cells, NK cells, and monocytes/macrophages
- IL-2 mediates its biological activities by binding to IL-2 receptor compleses
- The intermediate affinity IL-2R is comprised of IL-2Rβ (CD122) and common gamma chain (γc; CD132) subunits whereas the high-affinity IL-2R is comprised of IL-2Rα (CD25), IL-2Rβ and γc subunits
- The JES6-5H4 monoclonal antibody binds to IL-2 and neutralizes its biological activity
- This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™
- PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics
- Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488nm), green (532nm) and yellow-green (561nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20nm filter)
- Host Species: Rat Clone: JES6-5H4 Isotype: IgG2b Species Reactivity: Mouse Immunogen: Mouse IL-2 Recombinant Protein Intracellular Staining