BDB562542

IL-17A Rat anti-Mouse, PE-CF594, Clone: TC11-18H10, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562542-Each-of-1 In Stock ₹ 23,451.50

BDB562542 - Each of 1

₹ 23,451.50

In Stock

Quantity

1

Base Price: ₹ 23,451.50

GST (18%): ₹ 4,221.27

Total Price: ₹ 27,672.77

Antigen

IL-17A

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Interleukin-17A; Il17a; Cytotoxic T-lymphocyte-associated antigen; CTLA-8

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

TC11-18H10

Conjugate

PE-CF594

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Recombinant Mouse IL-17A Protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Related Products

Img

BD Biosciences

BDB562933

--

Img

BD Biosciences

BDB563745

--

Img

BD Biosciences

BDB562483

--

Img

BD Biosciences

BDB563276

--

Img

BD Biosciences

BDB564145

--

Img

BD Biosciences

BDB564802

--

Img

BD Biosciences

BDB563774

--

Img

BD Biosciences

BDB564828

--

Description

  • The TC11-18H10 monoclonal antibody specifically binds to recombinant and natural mouse IL-17A proteins
  • IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses
  • Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells
  • It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo
  • The TC11-18H10 antibody has been reported to neutralize IL-17A activity
  • Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways
  • The mouse IL-17A cDNA was isolated from a cDNA library generated from TCRαβ+CD4-CD8- thymocytes
  • This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™
  • PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics
  • Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488nm), green (532nm) and yellow-green (561nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20nm filter)
  • Host Species: Rat Clone: TC11-18H10 Isotype: IgG1, κ Species Reactivity: Mouse Immunogen: Recombinant Mouse IL-17A Protein Intracellular Staining