BDB562544

LAP Mouse anti-Human, PerCP-Cy5.5, Clone: TW4-2F8, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562544-Each-of-1 In Stock ₹ 24,341.50

BDB562544 - Each of 1

₹ 24,341.50

In Stock

Quantity

1

Base Price: ₹ 24,341.50

GST (18%): ₹ 4,381.47

Total Price: ₹ 28,722.97

Antigen

LAP

Classification

Monoclonal

Conjugate

PerCP-Cyanine5.5

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human TGF-β1

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

TW4-2F8

Description

Latency-associated peptide; TGFB1; TGFbeta; Transforming growth factor beta

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The TW4-2F8 monoclonal antibody specifically binds to Latency-Associated Peptide (LAP), a component of the dimeric Transforming Growth Factor-beta 1 (TGF-β1) propeptide encoded by TGFB1
  • Prior to secretion, the dimeric LAP-TGF-β1 propeptide is cleaved resulting in a biologically inactive form of dimeric TGF-β1 that is noncovalently associated with dimeric LAP (latent TGF-β1)
  • This complex may be expressed on the surface of TGF-β1TGF-β1
  • TGF-β1 is a potent multifunctional cytokine that regulates numerous processes including development, hematopoiesis, tissue remodeling, wound repair, and immunity as well as cancer and autoimmune diseases
  • Clone TW4-2F8 is routinely quality tested through intracellular staining of LAP in P3UI-TGFβ1 transfected cells.