BDB563143
LAP Mouse anti-Mouse, PE, Clone: TW7-16B4, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563143-Each-of-1 | In Stock | ₹ 24,341.50 |
BDB563143 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,341.50
GST (18%): ₹ 4,381.47
Total Price: ₹ 28,722.97
Antigen
LAP
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Latency-associated peptide; TGFB1; TGFbeta; Transforming growth factor beta
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
TW7-16B4
Conjugate
PE
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse TGF-β1 Transfected Cells
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The TW7-16B4 monoclonal antibody speci fically binds to Latency-Associated Peptide (LAP), a component of the dimeric Transforming Growth Factor-beta 1 (TGF-β1) propeptide encoded by Tgfb1
- Prior to secretion, the dimeric LAP-TGF-β1 propeptide is cleaved resulting in a biologically inactive form of dimeric TGF-β1 that is noncovalently associated with dimeric LAP (latent TGF-β1)
- This complex may be expressed on the surface of TGF-β1-producing cells or be further processed by proteolytic removal of LAP to release the biologically active mature form of the soluble TGF-β1 homodimer
- Platelets contain TGF-β1 and most nucleated cells, including tumor cells and cells that comprise the innate and adaptive immune system can produce TGF-β1
- TGF-β1 is a potent multifunctional cytokine that regulates numerou s processes including development, hematopoiesis, tissue remodeling, wound repair, and immunity as well as cancer and autoimmune diseases.