BDB562555

CD197 (CCR7) Mouse anti-Human, Brilliant Violet 421, Clone: 150503, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562555-Each-of-1 In Stock ₹ 33,998.00

BDB562555 - Each of 1

₹ 33,998.00

In Stock

Quantity

1

Base Price: ₹ 33,998.00

GST (18%): ₹ 6,119.64

Total Price: ₹ 40,117.64

Antigen

CD197

Classification

Monoclonal

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human CCR7 Transfected Cell Line

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

150503

Description

CC chemokine receptor 7; BLR2; CMKBR7; EBI1; EVI1; MIP-3 beta receptor

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a

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Description

  • The monoclonal antibody 150503 specifically binds to the human CC chemokine receptor, CCR7, also known as CD197
  • CCR7 (previously known as BLR2, EBI1 and CMKBR7), a seven-transmembrane, G-protein-coupled receptor, is the specific receptor for CC chemokines, MIP-3β/Exodus 3/ELC/ CCL19 and 6Ckine/Exodus 2/SLC/TCA4/CCL21
  • CCR7 mRNA is expressed mainly in lymphoid tissues including spleen, lymph nodes and tonsil
  • CCR7 is expressed on peripheral T and B lymphocytes, by bone marrow and cord blood CD34-positive cells and by mature dendritic cells
  • Differential CCR7 expression can be used to distinguish naive, central memory and effector memory T cell subsets
  • The human CCR7 gene, unlike other CC chemokine receptor genes, has been mapped to chromosome 17 (region 17q12)
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
  • With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon™ BV421can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
  • BD Horizon™ BV421conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.