BDB563167
CD27 Mouse anti-Human, Brilliant Violet 711, Clone: L128, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563167-Each-of-1 | In Stock | ₹ 29,681.50 |
BDB563167 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,681.50
GST (18%): ₹ 5,342.67
Total Price: ₹ 35,024.17
Antigen
CD27
Classification
Monoclonal
Conjugate
Brilliant Violet 711
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human Activated Peripheral Blood Cells
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
L128
Description
TNFRSF7; Tumor necrosis factor receptor superfamily, member 7; Tp55; S152
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1
Related Products
Description
- The L128 monoclonal antibody specifically binds to human CD27
- CD27 is a 55-kDa disulfide-linked dimer that is a member of the nerve growth factor (NGF) super family
- This family also includes CD40, rat OX40, tumor necrosis factor (TNF) receptors and CD95 (Fas)
- With its ligand CD70, CD27 acts in a co-stimulatory fashion on T lymphocytes
- Present on most peripheral blood T lymphocytes and medullary thymocytes, the CD27 antigen is upregulated upon activation with the release of a soluble form, 28 to 32 kDa
- It is also detected on a subpopulation of approximately 33% of circulating B lymphocytes
- Following exposure to antigens, CD45RA+ T lymphocytes respond by upregulating the CD27 antigen
- After maximal stimulation, the CD27 antigen cannot be re-expressed on long-term cultures or on CD45RA-CD27+ T lymphocytes
- The CD4+CD27- population is contained within the memory CD45RO+ subset that proliferates after exposure to allergens
- Two subpopulations of B lymphocytes bearing the CD27 antigen secrete IgM ( δ +) and IgG ( δ -).