BDB563456
CD40 Mouse anti-Human, Brilliant Violet 510, Clone: 5C3, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563456-Each-of-1 | In Stock | ₹ 27,234.00 |
BDB563456 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,234.00
GST (18%): ₹ 4,902.12
Total Price: ₹ 32,136.12
Antigen
CD40
Classification
Monoclonal
Conjugate
Brilliant Violet 510
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
5C3
Description
TNFRSF5; TNF receptor superfamily member 5; CD40L receptor; Bp50; p50
Host Species
Mouse
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- This 5C3 monoclonal antibody specifically binds to CD40, a 45-48 kDa type I integral membrane glycoprotein
- CD40 is expressed on B lymphocytes, but is not expressed on terminally differentiated B cells
- CD40 is also expressed by endothelial cells, basal epithelial cells and some epithelial cell carcinomas, follicular dendritic cells, macrophages, fibroblasts, keratinocytes, and CD34+ hematopoietic progenitor cells
- This antibody is useful for studying the roles played by CD40 in B-cell growth, proliferation, and differentiation including immunoglobulin isotype switching
- Anti-CD40 antibodies have been reported to stimulate B-cell proliferation when costimulated with anti-µ, anti-CD20 antibodies or with phorbol esters
- 5C3 is capable of inducing B-cell proliferation when presented with IL-4
- The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
- With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon™ BV510 can be excited by the violet laser and detected in the BD Horizon™ V500 (525/50-nm) filter set
- BD Horizon™ BV510 conjugates are useful for the detection of dim markers off the violet laser.