BDB563739
CD274 Mouse anti-Human, Brilliant Violet 786, Clone: MIH1, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563739-Each-of-1 | In Stock | ₹ 39,872.00 |
BDB563739 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,872.00
GST (18%): ₹ 7,176.96
Total Price: ₹ 47,048.96
Antigen
CD274
Classification
Monoclonal
Conjugate
Brilliant Violet 786
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human B7-H1 Transfected Cell Line
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
MIH1
Description
B7-H1; Programmed death ligand 1; PD-L1; PDCD1 ligand 1; PDCD1L1; PDCD1LG1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The MIH1 monoclonal antibody specifically binds to CD274, also known as Programmed Death Ligand 1 (PD-L1) and B7 Homolog 1 (B7-H1)
- CD274/PD-L1 and CD273/PD-L2 are members of the B7 family within the Immunoglobulin superfamily
- These type I transmembrane glycoproteins function as ligands for CD279, likewise known as the Programmed Death 1 (PD-1) receptor
- CD274 is expressed on activated dendritic cells, macrophages and T cells
- Studies show some overlapping functions of CD274 and CD273 and indicate an important role for CD279 and its ligands in regulating T and B cell responses
- CD274 is also expressed on placental trophoblasts, myocardial endothelium, cortical thymic epithelial cells, keratinocytes, and carcinomas
- The MIH1 antibody is reportedly a blocking antibody
- The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
- This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm
- BD Horizon™ BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).