BDB564175
CD127 Rat anti-Mouse, APC, Clone: SB/199, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564175-Each-of-1 | In Stock | ₹ 16,732.00 |
BDB564175 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,732.00
GST (18%): ₹ 3,011.76
Total Price: ₹ 19,743.76
Antigen
CD127
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Interleukin-7 receptor alpha chain; IL-7R alpha; IL-7RA; IL-7Rα; Il7r
Immunogen
BALB/c mouse pre-B cell line 1A9
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
SB/199
Conjugate
APC
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2b κ
Related Products
Description
- The SB/199 monoclonal antibody specifically binds to mouse CD127, the 65-75 kDa type-I transmembrane protein IL-7R α
- The high affinity IL-7 receptor complex is composed of at least two transmembrane proteins, IL-7R α and CD132, the common γchain
- CD127 has some sequence homology to the cytokine receptor superfamily (also known as the hematopoietin receptor superfamily)
- Mice lacking CD127 display profoundly impaired development of the B and T lymphoid cell lineages, but display no obvious non-lymphoid abnormalities
- IL-7R α is expressed on common lymphoid progenitors and early stages of B lineage development in the bone marrow, on the earliest thymocyte progenitors, on CD4-CD8- double-negative and CD4+ and CD8+ single-positive thymocytes, and on most peripheral T lymphocytes
- Intestinal intraepithelial lymphocytes with low-density γδ TCR upregulate CD127 expression in response to IL-2, which may be secreted by neighboring αβ TCR-bearing T cells.