BDB564409

Cardiac Troponin I Mouse, Alexa Fluor 647, Clone: C5, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564409-Each-of-1 In Stock ₹ 28,791.50

BDB564409 - Each of 1

₹ 28,791.50

In Stock

Quantity

1

Base Price: ₹ 28,791.50

GST (18%): ₹ 5,182.47

Total Price: ₹ 33,973.97

Antigen

Cardiac Troponin I

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human, Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

C5

Description

cTnI, TNNI3, TNNC1

Immunogen

Human

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The C5 monoclonal antibody specifically binds to Cardiac Troponin I (cTnI)
  • cTnI is a ∽30-kDa protein that is also known as TNNI3 and TNNC1
  • Troponin I is the inhibitory subunit of Troponin, which also contains the subunits Troponin C and Troponin T
  • Troponin aids the Ca[2+]-dependent interaction of actin and myosin, which are the main contracile components in muscle cells
  • cTnI is specifically expressed in cardiac tissue, while skeletal troponin I is expressed in skeletal muscle in slow and fast isoforms
  • Hereditary cardiomyopathy is associated with mutations in cTnI
  • During product development, the purified C5 monoclonal antibody detected cTnI by western blot analysis of cellular lysates and flow cytometric analysis of fixed and permeabilized cells.