BDB564769
CCR10 Mouse anti-Human, BB515, Clone: 1B5, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564769-Each-of-1 | In Stock | ₹ 24,341.50 |
BDB564769 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,341.50
GST (18%): ₹ 4,381.47
Total Price: ₹ 28,722.97
Antigen
CCR10
Classification
Monoclonal
Concentration
0.2mg/mL
Description
C-C CKR-10, C-C CKR-10, G-protein coupled receptor 2, CCR-10, GPR2
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
1B5
Conjugate
Brilliant Blue 515 (BB515)
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen
Human CCR10 Transfected Cell Line
Quantity
25 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 1B5 monoclonal antibody specifically binds to CCR10 (CC-chemokine receptor 10)
- CCR10 is a seven transmembrane domain G-protein-coupled receptor that is also known as GPR-2 (G-protein coupled receptor 2)
- CCR10 is expressed by cells that mediate epithelial immunity including a small subset of T memory cells, IgA-secreting B cells, dermal endothelial cells and fibroblasts
- It is also expressed on EBV-immortalized B cells
- Chemokine CCL27 and CCL28 are the ligands for CCR10
- CCR10 reportedly not only functions in regulating the homing and function of cells that mediate epithelial immunity
- It may also regulate the epithelial localization, survival, and proliferation of tumor cells and facilitate their evasion from immune surveillance
- The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences
- With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (eg, 530/30-nm filter)
- This dye provides a much brighter alternative to FITC with less spillover into the PE detector.