BDB564774
CD96 Mouse anti-Human, BB515, Clone: 6F9, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564774-Each-of-1 | In Stock | ₹ 39,160.00 |
BDB564774 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,160.00
GST (18%): ₹ 7,048.80
Total Price: ₹ 46,208.80
Antigen
CD96
Classification
Monoclonal
Conjugate
Brilliant Blue 515 (BB515)
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen
Human CD96 Transfected Cell Line
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
6F9
Description
TACTILE; T cell activation increased late expression
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The 6F9 monoclonal antibody specifically binds to human CD96, also known as TACTILE (T cell activation increased late expression)
- CD96 is a type I transmembrane glycoprotein and member of the Ig superfamily
- CD96 is expressed at low levels on resting natural killer (NK) cells and T cells and at high levels on activated NK and T cells
- CD96 is also expressed on some T-cell leukemia and acute myeloid leukemia cells
- CD96 may serve as a marker for acute myelogenous leukemia stem cells
- CD96 plays a role in the adhesive interactions of activated NK and T cells during immune responses
- CD96 binds to the poliovirus receptor (CD155) that is highly expressed by some tumor cells
- CD155-mediated ligation of CD96 can induce NK cell-mediated cytotoxicity
- CD96-mediated uptake of CD155 may adversely affect NK cells and thus reduce their effectiveness in anti-tumor responses
- The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences
- With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (eg, 530/30-nm filter)
- This dye provides a much brighter alternative to FITC with less spillover into the PE detector.