BDB566261

CD107A Mouse anti-Human, Brilliant Violet 421, Clone: H4A3, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB566261-Each-of-1 In Stock ₹ 19,046.00

BDB566261 - Each of 1

₹ 19,046.00

In Stock

Quantity

1

Base Price: ₹ 19,046.00

GST (18%): ₹ 3,428.28

Total Price: ₹ 22,474.28

Antigen

CD107A

Clone

H4A3

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Classification

Monoclonal

Conjugate

Brilliant Violet 421

Gene Alias

LAMP1, LAMP-1, LAMPA, LGP120

Immunogen

Human Adult Adherent Peripheral Blood Cells

Quantity

25 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The H4A3 monoclonal antibody specifically binds to the heavily glycosylated 110 kDa Lysosomal-associated membrane protein 1, LAMP-1
  • LAMP-1 is a widely expressed intracellular antigen
  • It is also expressed on the surface of activated platelets, PHA-activated lymphocytes, cytotoxic T cells and NK cells, and some tumor cell lines, including U937 and KG1a
  • LAMP-1 has been shown to be a ligand for E-selectin-mediated cell adhesion
  • LAMP-1 and LAMP-2 (CD107b) are carriers for poly-N-acetyllactosamines and are able to display sialyl Le[x] termini
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
  • With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter)
  • BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences
  • Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates
  • Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.