BDB566266
CD137 Mouse anti-Human, Brilliant Violet 421, Clone: 4B4-1, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB566266-Each-of-1 | In Stock | ₹ 19,135.00 |
BDB566266 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 19,135.00
GST (18%): ₹ 3,444.30
Total Price: ₹ 22,579.30
Antigen
CD137
Clone
4B4-1
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Classification
Monoclonal
Conjugate
Brilliant Violet 421
Gene Alias
4-1BB
Immunogen
Recombinant Human 4-1BB Fusion Protein
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The 4B4-1 monoclonal antibody specifically binds to CD137 which is also known as 4-1BB, and ILA (induced by lymphocyte activation)
- CD137 is a type I transmembrane glycoprotein that belongs to the TNF/NGF receptor family
- It is encoded by TNFRSF9 /(tumor necrosis factor receptor superfamily, member 9)
- CD137 is expressed on activated T cells, B cells, monocytes, and follicular dendritic cells
- CD137 plays roles in the costimulation, differentiation and survival of T cells and B cells The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant Violet™ family of dyes
- With an Ex Max of 407nm and Em Max at 421nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter)
- BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates
- BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences
- Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates
- Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.