BDB610512
LRP Mouse, Unlabeled, Clone: 42, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB610512-Each-of-1 | In Stock | ₹ 23,629.50 |
BDB610512 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,629.50
GST (18%): ₹ 4,253.31
Total Price: ₹ 27,882.81
Antigen
LRP
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Bovine, Canine, Human, Rabbit
Isotype
IgG1
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
42
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- Drugs that selectively attack dividing cells are often used in cancer therapy
- However, small cell populations do not die, but develop resistance to a variety of toxic drugs
- Multidrug resistance is achieved by gene amplification of specific membrane-bound transport ATPases that shuttle the drugs out of cells
- Some multidrug-resistant cancer cells express a protein of 110 kDa named LRP ( L ung R esistance-related P rotein)
- LRP expression might be an indicator of prognosis after chemotherapy in acute myeloid leukemia and ovarian carcinoma
- The LRP gene encodes a protein of 896 amino acids with significant homology to the major vault protein from Dictyostelium discoideum
- Although ubiquitously expressed, LRP is most abundant in epithelial cells.