BDB740001

IL-10Rbeta (CD210b) Mouse anti-Human, Brilliant Violet 421, Clone: 90220, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740001-Each-of-1 In Stock ₹ 49,528.50

BDB740001 - Each of 1

₹ 49,528.50

In Stock

Quantity

1

Base Price: ₹ 49,528.50

GST (18%): ₹ 8,915.13

Total Price: ₹ 58,443.63

Antigen

IL-10Rbeta (CD210b)

Classification

Monoclonal

Concentration

0.2mg/mL

Description

IL-10R2; IL-10RB; IL-10Rβ; IL10RB; IL-10 Receptor beta; CRFB4

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

90220

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human IL-10 Rβ Recombinant Protein

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 90220 monoclonal antibody specifically binds to the beta subunit (IL-10R beta/IL-10RB/IL-10R β ) of the heteromeric IL-10 Receptor complex
  • This type I transmembrane glycoprotein is also known as, subunit 2 (IL-10R2) or CD210b
  • The IL-10 Receptor complex is formed by the binding of dimeric IL-10 to two cell surface alpha subunits of the IL-10 Receptor (CD210a/IL-10RA/IL-10R α )
  • This complex can then recruit two CD210b subunits resulting in the transduction of intracellular JAK/STAT pathway signals
  • CD210b is also a component of cytokine receptor complexes specific for IL-22, IL-26, IL-28 and IL-29
  • CD210b is expressed by a variety of cell types including T cells, B cells, NK cells, monocytes and macrophages
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
  • BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.