BDB740220
CD69 Hamster anti-Mouse, BUV395, Clone: H1.2F3, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB740220-Each-of-1 | In Stock | ₹ 35,600.00 |
BDB740220 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,600.00
GST (18%): ₹ 6,408.00
Total Price: ₹ 42,008.00
Antigen
CD69
Classification
Monoclonal
Concentration
0.2mg/mL
Description
VEA; Very Early Activation Antigen; AIM; Activation Induced Molecule
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG1 λ3
Applications
Flow Cytometry
Clone
H1.2F3
Conjugate
Brilliant Ultraviolet 395
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse Dendritic Epidermal T Cell Line Y245
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The H1.2F3 monoclonal antibody specifically binds to CD69 (Very Early Activation antigen), an 85 kDa disulfide-linked homodimer of differentially glycosylated subunits
- CD69 is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules
- Its expression is rapidly induced upon activation of lymphocytes (T, B, NK, and NK-T cells), neutrophils, and macrophages
- CD69 is expressed also on thymocytes that are undergoing positive selection; its role in that process is unclear
- H1.2F3 mAb augments PMA-induced T-cell stimulation and IFN- γ-induced macrophage stimulation
- IL-2-activated NK cells express CD69, and H1.2F3 mAb induces redirected lysis of FcR-bearing target cells by NK cells
- The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
- This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
- With an Ex Max at 348nm and an Em Max at 395nm, BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.