PAPPA Monoclonal Antibody (004-09), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BTE0040902-Each-of-1 | In Stock | ₹ 85,662.50 |
BTE0040902 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 85,662.50
GST (18%): ₹ 15,419.25
Total Price: ₹ 1,01,081.75
Antigen
PAPPA
Classification
Monoclonal
Concentration
0.96 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
Q13219
Gene Symbols
PAPPA
Immunogen
Purified human PAPP-A.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b κ
Applications
ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone
004-09
Conjugate
Unconjugated
Gene
PAPPA
Gene Alias
8430414N03Rik; ASBABP2; aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; DIPLA1; IGFBP-4 ase; IGFBP-4ase; IGF-dependent IGFBP-4 protease; insulin-like growth factor-dependent IGF binding protein-4 protease; insulin-like growth factor-dependent IGF-binding protein 4 protease; PAG1; PAPA; PAPP A; PAPPA; PAPP-A; PAPPA1; Pappalysin; pappalysin 1; pappalysin-1; pregnacy-associated plasma protein A; pregnancy-associated plasma protein A; pregnancy-associated plasma protein A, pappalysin 1; RP11-45A16.1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5069
Content And Storage
4° C, store in dark
Form
Liquid
Related Products
Description
- BTE 004-09-02 detects Pregnancy-associated plasma protein A (PAPP-A) from human samples
- Heat and SDS denatured PAPP-A is also recognized, but not acid treated PAPP-A
- BTE 004-09-02 has been successfully used in ELISA, Western blotting and Immunohistochemistry procedures
- In sandwich ELISA the optimal combination is BTE 004-09-02 used as coating antibody and biotinylated ABS 006-24-02 used as detection antibody
- BTE 004-09-02 can also be used as detection antibody in sandwich ELISA in combination with a polyclonal antibody towards PAPP-A in coat
- BTE 004-09-02 detect both reduced and unreduced PAPP-A in Western Blotting, though reaction to unreduced is less than that of ABS 006-01-02 and ABS 006-24-02
- The epitope of BTE 004-09-02 is different from ABS 006-01-02 and ABS 006-24-02
- The epitope is located on the PAPP-A subunit of the heterotetramer
- NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women
- The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits
- Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).