CSI0030202

Vitronectin Monoclonal Antibody (HV2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 CSI0030202-Each-of-1 In Stock ₹ 85,217.50

CSI0030202 - Each of 1

₹ 85,217.50

In Stock

Quantity

1

Base Price: ₹ 85,217.50

GST (18%): ₹ 15,339.15

Total Price: ₹ 1,00,556.65

Antigen

Vitronectin

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P04004

Gene Symbols

VTN

Immunogen

Human vitronectin purified from plasma by heparin-affinity chromatography.

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

HV2

Conjugate

Unconjugated

Gene

VTN

Gene Alias

Aa1018; AI256434; complement S-protein; epibolin; extracellular matrix protein; glycoprotein 66; serum spreading factor; serum-spreading factor; somatomedin B; Somatomedin-B; S-protein; V75; Vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S-protein); Vitronectin V10 subunit; Vitronectin V65 subunit; VN; VNT; VTN

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7448

Content And Storage

4° C, store in dark

Form

Liquid

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Description

  • CSI 003-02-02 is highly specific for vitronectin
  • There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin)
  • CSI 003-02-02 is human-specific (no reactivity with cat, dog, cow, sheep, goat, pig, rabbit, horse)
  • CSI 003-02-02 has been successfully used in ELISA, immunohistochemistry, and Western blotting techniques
  • CSI 003-02-02 can be used to purify vitronectin from human plasma by affinity chromatography
  • It can also be used to quantitatively affinity-deplete human plasma or serum of vitronectin
  • It partially denatures vitronectin upon antibody binding
  • It binds equally well to native and denatured vitronectin and can be used to quantitate vitronectin in human plasma in a sandwich ELISA with CSI 003-02-02
  • It does not interfere with the binding of any known vitronectin ligands
  • The epitope of CSI 003-02-02 is located in the connecting region
  • Binding can be competed selectively by a peptide comprising aa 121-133
  • NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL VTN is a member of the pexin family
  • This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors
  • The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.