FEMA549775

Phospho-AKT1 (Ser473) Recombinant Rabbit Monoclonal Antibody (4H12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549775-Each-of-1 In Stock ₹ 37,202.00

FEMA549775 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

Phospho-AKT1 (Ser473)

Classification

Recombinant Monoclonal

Concentration

0.8 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P31749

Gene Symbols

AKT1

Immunogen

A synthesized peptide derived from human Phospho-AKT1 (Ser473)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

4H12

Conjugate

Unconjugated

Gene

AKT1

Gene Alias

Akt, Akt kinase, AKT serine/threonine kinase 1, Akt/PKB, akt1, AKT1 kinase, AKT1m, Akt1m protein, Akt1-PA, Akt1-PB, Akt1-PC, Akt1-PD, Akt1-PE, CAKT, C-AKT, CG4006, CG4006-PA, CG4006-PB, CG4006-PC, CG4006-PD, CG4006-PE, CWS6, dAkt, D-Akt, dAkt kinase, dAKT/dPKB, dAkt/PKB, DAKT1, DAKT1/PKB, Dmel\CG4006, Dmel_CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, l(3)04226, l(3)89Bq, murine thymoma viral (v-akt) oncogene homolog 1, pAkt, P-AKT, PKB, PKB alpha, PKB beta, PKB gamma, PKB/AKT, PKB/dAKT, PKBalpha, PKB-ALPHA, PKBG, PRKBA, protein kinase B, Protein kinase B alpha, protein kinase B-alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC protein kinase alpha RAC-PK alpha, RAC serine/threonine protein kinase, RAC serine/threonine-protein kinase, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RacPK, RAC-PK-alpha, RAC-PK-beta, RAC-PK-gamma, related to A and C kinases, related to PKA to PKC protein kinases, related to the A and C kinases, SD10374p, serine/threonine protein kinase, serine-threonine protein kinase, Thymoma viral proto-oncogene, thymoma viral proto-oncogene 1, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

207

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • AKT1 (PKB alpha) is a serine/threonine kinase that regulates cell survival
  • The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells
  • This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors
  • Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9
  • The AKT pathway is a major target for cancer drug discovery.