FEMA549885

B-Raf Recombinant Rabbit Monoclonal Antibody (6G3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549885-Each-of-1 In Stock ₹ 37,202.00

FEMA549885 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

B-Raf

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P15056

Gene Symbols

BRAF

Immunogen

A synthesized peptide derived from human B Raf

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

6G3

Conjugate

Unconjugated

Gene

BRAF

Gene Alias

94 kDa B-raf protein, 9930012E13Rik, AA120551, AA387315, AA473386, Braf, B-raf, B-raf protein, B-raf protein isoform 1, B-raf protein isoform 2, B-Raf proto-oncogene serine/threonine-protein kinase, B-Raf proto-oncogene serine/threonine-protein kinase (p94), B-Raf proto-oncogene, serine/threonine kinase, Braf transforming gene, BRAF1, B-RAF1, Braf2, Braf-2, C230098H17, C87398, C-RMIL, D6Ertd631e, FLJ95109, MGC126806, murine sarcoma viral (v-raf) oncogene homolog B1, NS7, p94, Proto-oncogene B-Raf, proto-oncogene c-Rmil, RAFB1, RMIL, rmil serine/threonine-protein kinase, serine/threonine kinase, serine/threonine-protein kinase B-raf, Serine/threonine-protein kinase Rmil, v-raf murine sarcoma viral oncogene homolog B, v-raf murine sarcoma viral oncogene homolog B1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

673

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus
  • It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron
  • This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion
  • Mutations in B-Raf have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung
  • A pseudogene, which is located on chromosome X, has been identified for B-Raf.