Lamin A Recombinant Rabbit Monoclonal Antibody (4H7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549796-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA549796 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
Lamin A
Classification
Recombinant Monoclonal
Concentration
0.6 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P02545
Gene Symbols
LMNA
Immunogen
A synthesized peptide derived from human LMNA
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone
4H7
Conjugate
Unconjugated
Gene
LMNA
Gene Alias
70 kDa lamin, CDCD1, CDDC, CMD1A, CMT2B1, Dhe, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, lamin, lamin A, lamin A/C, lamin A/C-like 1, lamin C, lamin C2, lamin-A/C, LDP1, LFP, LGMD1B, LMN1, Lmna, LMNA protein, LMNC, LMNL1, OTTHUMP00000015843, OTTHUMP00000015846, OTTHUMP00000015847, Prelamin-A/C, PRO1, renal carcinoma antigen NY-REN-32, unnamed protein product
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4000
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane
- Two main subtypes of nuclear lamins can be distinguished, i.e
- A-type lamins and B-type lamins
- The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e
- lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e
- lamin B1 and lamin B2
- Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy
- In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins.