FEMA549847

RPE65 Recombinant Rabbit Monoclonal Antibody (7B10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549847-Each-of-1 In Stock ₹ 37,202.00

FEMA549847 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

RPE65

Classification

Recombinant Monoclonal

Concentration

1.6 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q16518

Gene Symbols

RPE65

Immunogen

A synthesized peptide derived from human RPE65

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

7B10

Conjugate

Unconjugated

Gene

RPE65

Gene Alias

65kDa, A930029L06Rik, all-trans-retinyl-palmitate hydrolase, BCO family, member 3, BCO3, LCA2, Lutein isomerase, membrane receptor p63, meso-zeaxanthin isomerase, modifier of retinal degeneration 1, Mord1, mRPE65, p63, RBP-binding membrane protein, rd12, retinal pigment epithelium 65, retinal pigment epithelium 65-like, retinal pigment epithelium abundant protein RPE65, retinal pigment epithelium specific protein 65, retinal pigment epithelium, 65 kDa, retinal pigment epithelium-specific 65 kDa protein, retinal pigment epithelium-specific 65kD protein, retinal pigment epithelium-specific protein (65kD), retinal pigment epithelium-specific protein 65kDa, retinal pigment epithelium-specific protein RPE65, Retinitis pigmentos, retinitis pigmentosa 20 (autosomal recessive), retinoid isomerohydrolase, retinoid isomerohydrolase RPE65, retinol isomerase, RP20, RPE65, rpe65 gene for retinal pigment epithelium-specific protein, RPE65, retinoid isomerohydrolase, sRPE65, truncated RPE65

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6121

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • RPE65 is a major protein of the retinal pigment epithelium (RPE)
  • RPE65 is essential for the regeneration of rhodopsin in the visual cycle
  • Mutations in RPE65 are responsible for certain forms of autosomal recessive severe retinal dystrophy, including Leber Congenital Amaurosis (LCA)
  • Loss of function results in a block in retinoid processing required for the synthesis of 11-cis retinal and the accumulation of retinyl esters in the RPE.