FEMA549883

PAK2 Recombinant Rabbit Monoclonal Antibody (6D12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549883-Each-of-1 In Stock ₹ 37,202.00

FEMA549883 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

PAK2

Classification

Recombinant Monoclonal

Concentration

0.53 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q13177, Q64303, Q8CIN4

Gene Symbols

Pak2

Immunogen

A synthesized peptide derived from human PAK2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunoprecipitation, Western Blot

Clone

6D12

Conjugate

Unconjugated

Gene

Pak2

Gene Alias

5330420P17Rik, A130002K10Rik, AI836325, Alpha-PAK, Beta-PAK, C-t-PAK2, D16Ertd269e, gamma pak, gamma-PAK, mKIAA4182, Oligophrenin-3, OPHN3, p21 (CDKN1A)-activated kinase 2, p21 (RAC1) activated kinase 2, p21 protein (Cdc42/Rac)-activated kinase 2, p21-activated kinase 2, p27, p34, p58, p65-PAK, PAK alpha, PAK beta, PAK gamma, PAK1, PAK-1, Pak2, PAK-2, PAK-2p27, PAK-2p34, PAK3, PAK-3, PAK65, PAKgamma, S6/H4 kinase, serine/threonine-protein kinase PAK 2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

224105, 29432, 5062

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • PAK2 (serine/threonine-protein kinase PAK2) is a serine/threonine kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, or proliferation
  • It acts as a downstream effector of the small GTPases CDC42 and RAC1
  • Activation by the binding of active CDC42 and RAC1 results in a conformation change and a subsequent autophosphorylation on several serine and/or threonine residues
  • Full-length PAK2 stimulates cell survival and cell growth
  • PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling
  • PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities.