FEMA549958

SOX9 Recombinant Rabbit Monoclonal Antibody (5H12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549958-Each-of-1 In Stock ₹ 37,202.00

FEMA549958 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

SOX9

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P48436

Gene Symbols

SOX9

Immunogen

A synthesized peptide derived from human SOX9

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

5H12

Conjugate

Unconjugated

Gene

SOX9

Gene Alias

2010306G03Rik, AV220920, CMD1, CMPD1, mKIAA4243, SOX 9, Sox9, SOX-9, Sox9 transcription factor, SRA1, SRXX2, SRXY10, SRY (sex determining region Y)-box 9, SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal), SRY (sex determining region Y)-box9, SRY (sex-determining region Y)-box 9 protein, SRY box 9, SRY-box 9, SRY-Box 9 , SRY-box containing 9, SRY-box containing gene 9, SRY-box containing protein 9, SRY-box transcription factor 9, SRY-related HMG-box, gene 9, transcription activator Sox9, transcription factor SOX-9

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6662

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • SOX9 has a role in sex determination and differentiation of Sertoli cells
  • It is involved in chondrogenesis and regulates the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes
  • Translocation of this gene can cause campomelic dysplasia
  • SOX9 is involved in the formation of testes from the indifferent fetal gonads
  • It is a major molecular component of the neuron-glia switch in developing spinal cord
  • During normal development, SOX9 allows the prostate epithelium to outgrow into the mesenchyme and then provides basal cell support for development and maintenance of the luminal epithelium
  • These functions of SOX9 are subverted in prostate cancer to support tumor growth and invasion
  • SOX9 may direct the formation of neural crest precursors and the development of a range of neural crest derivative
  • It has a transcriptional regulation in melanin production in cells
  • Northern blot analysis shows its expression on adult testis, adult heart, and fetal brain.