FEMA550695

SOX2 Recombinant Rabbit Monoclonal Antibody (PO00-28), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550695-Each-of-1 In Stock ₹ 42,275.00

FEMA550695 - Each of 1

₹ 42,275.00

In Stock

Quantity

1

Base Price: ₹ 42,275.00

GST (18%): ₹ 7,609.50

Total Price: ₹ 49,884.50

Antigen

SOX2

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P48431, P48432

Gene Symbols

SOX2

Immunogen

Recombinant protein within human SOX2 aa 1-317/317.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

PO00-28

Conjugate

Unconjugated

Gene

SOX2

Gene Alias

ANOP3, cb236, Delta EF2a, lcc, MCOPS3, MCOPS3 (Microphthalmia Syndromic type 3), RGD1565646, sex determining region Y-box 2, SOX 2, SOX2, Sox-2, soxp, SRY (sex determining region Y) box 2, SRY (sex determining region Y)-box 2, SRY box 2, SRY related HMG box 2, SRY-box 2, SRY-box 2, SOX2, SRY-box containing gene 2, SRY-box transcription factor 2, SRY-related HMG-box gene 2, transcription factor SOX2, transcription factor SOX-2, wu:fb83g04, wu:fc14d07, ysb, zgc:65860, zgc:77389

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

20674, 499593, 6657

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Positive control: Human cervical carcinoma tissue, human glioma tissue, human esophagus tissue, human tonsil tissue, human lung carcinoma tissue, human trachea tissue, F9 cell lysates, F9, mouse brain tissue, mouse lung tissue, rat brain tissue, rat hippocampus tissue
  • Predicted band size: 34 kDa Subcellular Location: Nucleus
  • SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate
  • The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach
  • The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT)
  • Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins
  • Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.