NTHL1 Recombinant Rabbit Monoclonal Antibody (22H10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550067-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA550067 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
NTHL1
Classification
Recombinant Monoclonal
Concentration
1.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P78549
Gene Symbols
NTHL1
Immunogen
A synthesized peptide derived from human NTHL1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
22H10
Conjugate
Unconjugated
Gene
NTHL1
Gene Alias
bifunctional DNA N-glycoslyase/DNA-(apurinic or apyrimidinic site) lyase, Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase, DNA glycoslyase/AP lyase, DNA glycosylase/AP lyase, Endonuclease III-like protein 1, FAP3, hNTH1, nth (endonuclease III)-like 1 (E.coli), nth endonuclease III-like 1, Nth1, NTHL 1, Nthl1, nth-like DNA glycosylase 1, OCTS 3, OCTS3, thymine glycol DNA glycosylase/AP lyase
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4913
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- Oxygen radicals damage chromosonal DNA causing cell death and inducing mutations
- Although a major focus of oxidatively damaged DNA has centered on the repair of 8-oxo-G, a number of other damaged DNA sites are created by free-radical attack on DNA
- The human NTH1 repair protein is one enzyme that has been shown to act on a large number of these other oxidatively damaged DNA sites.A homologue of E
- coli Endonuclease III, NTH is a DNA glycosylase with apurinic/apyrimidinic lyase activity
- The NTH protein has broad substrate specificity, including numerous ring saturation and fragmentation products of pyrimidines
- Research indicates NTH plays a crucial role in removal of oxidative base lesions in mitochondrial DNA.