OGG1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APPA6505-Each-of-1 | In Stock | ₹ 48,905.50 |
APPA6505 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
OGG1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
OGG1
Gene Alias
8-hydroxyguanine DNA glycosylase; 8-oxoguanine DNA glycosylase; 8-oxoguanine DNA-glycosylase 1; 8-oxoguanine-DNA-glycosylase; AP lyase; DNA-(apurinic or apyrimidinic site) lyase; DNA-apurinic or apyrimidinic site lyase; HMMH; HOGG1; Mmh; MUTM; N-glycosylase/DNA lyase; OGG1; OGG1 type 1f; OGH1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100155036, 103345505, 18294, 4968, 81528
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O08760, O15527, O70249
Gene Symbols
OGG1
Immunogen
A peptide derived from the human Ogg1 (within amino acids 1-100).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Suggested positive control: Jurkat whole cell extracts
- 8-hydroxyguanine, a form of oxidative DNA damage induced by free radicals, causes G:C to T:A transversion
- In E
- Coli, three DNA repair enzymes exist to prevent the mutagenic effects of 8-hydroxyguanine
- One of these enzymes, MutM, was found to have a functional yeast (yOgg1) and human (hOgg1) homologue
- hOgg1 proteins efficiently released the 8-hydroxyguanine opposite the pyrimidine from DNA and cleaved the AP site in a manner similar to bacterial and yeast enzymes
- Genetic backgrounds in control of the repair of damaged DNA are involved in the susceptibility to cancer development
- The hOgg1 gene has been mapped to region 3p26
- 2, a region showing loss of heterozygosity (LOH) in a variety of cancers
- In particular, 3p25-p26 is a common LOH region in lung cancer.