FEMA550243

Connexin 26 Recombinant Mouse Monoclonal Antibody (24F5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550243-Each-of-1 In Stock ₹ 37,202.00

FEMA550243 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

Connexin 26

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.

P29033

Gene Symbols

Gjb2

Immunogen

Recombinant Human GJB2 protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone

24F5

Conjugate

Unconjugated

Gene

Gjb2

Gene Alias

AI325222, Cnx26, connexin 26, connexin-26, CX26, CXN-26, DFNA3, DFNA3A, DFNB1, DFNB1A, Gap junction beta-2 protein, gap junction channel protein connexin 26, gap junction membrane channel protein beta 2, gap junction protein beta 2, gap junction protein, beta 2, gap junction protein, beta 2, 26kDa, GJB2, Gjb-2, HID, KID, mutant gap junction protein beta 2, NSRD1, PPK

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2706

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication
  • Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family
  • GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels
  • Defects in GJB3 have been linked to erythrokeratodermia variables (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis
  • Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.