CRACC Recombinant Mouse Monoclonal Antibody (7H1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550260-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA550260 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
CRACC
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.
Q9NQ25
Gene Symbols
SLAMF7
Immunogen
Recombinant Human SLAMF7 protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone
7H1
Conjugate
Unconjugated
Gene
SLAMF7
Gene Alias
19A, 19A24, 19A24 protein, 4930560D03Rik, CD2 subset 1, CD2-like receptor activating cytotoxic cells, CD2-like receptor-activating cytotoxic cells, CD319, CRACC, CS1, Leukocyte cell-surface antigen, membrane protein FOAP-12, Novel Ly9, novel LY9 (lymphocyte antigen 9) like protein, protein 19A, RGD1560190, SLAM family member 7, SLAMF7, UNQ576/PRO1138
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
57823
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain
- Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway
- It may play a role in lymphocyte adhesion
- Isoform 3 does not mediate any activation
- SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro)
- SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea
- Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines
- The isoform 3 is expressed at much lower level than isoform 1
- There are three named isoforms.