CD223 Monoclonal Antibody (8B12E10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550268-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA550268 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
CD223
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.
P18627
Gene Symbols
LAG3
Immunogen
Recombinant Human Lymphocyte activation gene 3 protein (29-450AA)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
8B12E10
Conjugate
Unconjugated
Gene
LAG3
Gene Alias
Activation-induced cytidine deaminase-linked autoimmunity protein, Aida, CD223, FDC, LAG3, LAG-3, Ly66, lymphocyte activating 3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Secreted lymphocyte activation gene 3 protein, sLAG 3, sLAG3, sLAG-3, soluble LAG 3lymphocyte activating 3, soluble LAG3
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3902
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG1
Related Products
Description
- LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
- LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
- Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
- CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
- Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).