ROBO1 Recombinant Mouse Monoclonal Antibody (22D5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550262-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA550262 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
ROBO1
Classification
Recombinant Monoclonal
Concentration
0.55 mg/mL
Formulation
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.
Q9Y6N7
Gene Symbols
ROBO1
Immunogen
Recombinant Human ROBO1 protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone
22D5
Conjugate
Unconjugated
Gene
ROBO1
Gene Alias
AW494633, AW742721, deleted in U twenty twenty, DUTT1, FLJ21882, Gm310, HGNC:10249, H-Robo-1, MGC131599, MGC133277, ROBO1, roundabout 1, roundabout guidance receptor 1, roundabout homolog 1, roundabout homolog 1 (Drosophila), roundabout, axon guidance receptor, homolog 1, roundabout, axon guidance receptor, homolog 1 (Drosophila), Roundabout1 protein, SAX3
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6091
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- Specialized cells at the midline, which separates the left and right halves of the CNS, have a number of roles in directing growth cone behavior
- In the vertebrate spinal cord, the insect ventral nerve cord and in C
- elegans, midline cells produce guidance cues such as nectins and slit, which act as attractants and repellents, respectively
- These cells may act as gatekeepers to prevent axons from crossing the midline and to induce a switch in growth cone responsiveness to guidance cues beyond the gateway
- One such gatekeeper, Robo, is an axon guidance receptor that defines a novel subfamily of Ig superfamily proteins that are conserved from fruit flies to mammals
- Robo acts as a receptor for the repellent Slit and functions in a cell-autonomous fashion
- Non-crossing axons express high levels of Robo, whereas crossing axons express low levels of Robo before reaching the midline and high levels after they cross
- Robo1 and Robo2 are two human homologs of the Drosophila protein Roundabout
- Robo1 is also homologous to the C
- elegans gene sax3, whereas Robo2 is homologous to the zebrafish gene astray.