FEMA550224

GFAP Recombinant Mouse Monoclonal Antibody (6B12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550224-Each-of-1 In Stock ₹ 37,202.00

FEMA550224 - Each of 1

₹ 37,202.00

In Stock

Quantity

1

Base Price: ₹ 37,202.00

GST (18%): ₹ 6,696.36

Total Price: ₹ 43,898.36

Antigen

GFAP

Classification

Recombinant Monoclonal

Concentration

3.17 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.

P03995, P14136, P47819

Gene Symbols

GFAP

Immunogen

Recombinant Human GFAP protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

6B12

Conjugate

Unconjugated

Gene

GFAP

Gene Alias

6330404F12Rik, 65 kDa glutamic acid decarboxylase, AI836096, ALXDRD, Astrocyte or Intermediate Filament Protein, cb345, class III intermediate filament protein, etID36982.3, FLJ45472, GAD(65), Gad2, Gad-2, GAD65, GAD-65, GFAP, GFAP epsilon, gfap protein, gfapl, glial fibrillary acidic protein, Glial Fibrillary Acidic Protein (GFAP), glial fibrillary acidic protein alpha, glutamate decarboxylase 2, Glutamate decarboxylase 65 kDa isoform, glutamic acid decarboxylase 2, I79_011607, intermediate filament, intermediate filament protein, intermediate filament protein, GFAP, Unknown (protein for MGC:139638), wu:fb34h11, wu:fk42c12, xx:af506734, zgc:110485, zGFAP, intermediate filament protein, zrf-1 antigen

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14580, 24387, 2670

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG2a

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Description

  • GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family
  • GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves
  • In addition, neural stem cells strongly express GFAP
  • Antibodies to GFAP are very useful as markers of astrocytic cells
  • In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP
  • GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes
  • GFAP is used as a marker to distinguish astrocytes from other glial cells during development
  • Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system
  • Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.