FEMA550343

MAP2K4 Recombinant Rabbit Monoclonal Antibody (HL1888), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550343-Each-of-1 In Stock ₹ 41,385.00

FEMA550343 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

MAP2K4

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P45985, P47809

Gene Symbols

MAP2K4

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SEK1/MKK4. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

HL1888

Conjugate

Unconjugated

Gene

MAP2K4

Gene Alias

C-JUN N-terminal kinase kinase 1, dual specificity mitogen-activated protein kinase kinase 2, dual specificity mitogen-activated protein kinase kinase 4, dual specificity mitogen-activated protein kinase kinase 4, dual specificity mitogen-activated protein kinase kinase 4a, JNK kinase 1, JNK-activated kinase 1, JNK-activating kinase 1, JNKK, JNKK 1, JNKK1, MAP kinase activator 2, MAP kinase kinase 4, Map2k4, map2k4.L, map2k4a, map2k4-a, map2k4-b, MAP2K4delta, MAPK/ERK kinase 4, MAPKK 4, MAPKK4, MEK 4, MEK4, mitogen activated protein kinase kinase 4, mitogen activated protein kinase kinase 4, variant 1, mitogen-activated protein kinase kinase 4, mitogen-activated protein kinase kinase 4 L homeolog, mitogen-activated protein kinase kinase 4a, MKK4, mkk4a, MKK4A-l, PRKMK4, SAPK kinase 1, SAPK/ERK kinase 1, SAPK/Erk/kinase 1, SAPKK1, SAPKK-1, Sek1, Serk1, Skk1, Stress-activated protein kinase kinase 1, XELAEV_18044157mg, XMEK2, zgc:136500, zMKK4 protein

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

26398, 287398, 6416

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase 4) MEK4 or MKK4 is a dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38
  • MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs
  • MAP2K4 mediates a variety of physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines
  • MAP2K4 is important for carcinogenesis; a loss-off-function mutation in MAP2K4 was found in lung and pancreatic tumors
  • Conversely, a pro-oncogenic role was also found for MAP2K4.