FEMA550478

SynGAP Recombinant Rabbit Monoclonal Antibody (HL2292), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550478-Each-of-1 In Stock ₹ 41,385.00

FEMA550478 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

SynGAP

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

F6SEU4, Q9QUH6

Gene Symbols

SYNGAP1

Immunogen

Recombinant fragmemt of human SYNGAP1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

HL2292

Conjugate

Unconjugated

Gene

SYNGAP1

Gene Alias

DKFZp761G1421, Gm1963, KIAA1938, MRD5, Neuronal R, Neuronal RasGAP, OTTHUMP00000209046, p135 SynGAP, Ras GTPase-activating protein SynGAP, ras/Rap GTPase-activating protein SynGAP, RASA1, RASA5, synaptic Ras GTPase activating protein 1, synaptic Ras GTPase activating protein 1 homolog, synaptic Ras GTPase activating protein 1 homolog (rat), synaptic Ras GTPase activating protein, 135kDa, synaptic Ras GTPase-activating protein 1, Synaptic Ras-GAP 1, SYNGAP, Syngap1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

192117, 240057

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Synaptic Ras-GTPase activating protein (SynGAP) is a PDZ-domain interacting protein expressed almost exclusively in the brain
  • SynGAP has been shown to be a major component of postsynaptic density and associates with post synaptic density 95 kDa (PSD-95), a synaptic scaffold protein, and synaptic N-methyl-D-aspartate (NMDA) receptors
  • SynGAP Ras-GTPase activity has also been shown to be inhibited by phosphorylation by CaM kinase II, another abundant protein located in the postsynaptic density
  • It has been proposed that SynGAP may function as a negative regulator of MAP Kinase activation in the absence of active NMDA receptors.