K-Ras Monoclonal Antibody (A8E6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550603-Each-of-1 | In Stock | ₹ 41,741.00 |
FEMA550603 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,741.00
GST (18%): ₹ 7,513.38
Total Price: ₹ 49,254.38
Antigen
K-Ras
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P01116, P08644, P32883
Gene Symbols
KRAS
Immunogen
Recombinant protein within human KRAS aa 2-186/189.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
A8E6
Conjugate
Unconjugated
Gene
KRAS
Gene Alias
AI929937, cellular c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, CFC2, c-Ki-ras, c-Kirsten-ras protein, c-Kirsten-ras proto-oncogene, c-K-ras, c-K-ras2 protein, fa04e08, fc14b12, fc23g10, fj89d12, GTPase KRas, GTPase KRas, N-terminally processed, hypothetical protein LOC445289, K RAS, ki-Ras, Kirsten rat sarcoma oncogene 2, expressed, Kirsten rat sarcoma viral (Kras-2) oncogene homolog, Kirsten rat sarcoma viral oncogene, Kirsten rat sarcoma viral oncogene homolog, Kirsten rat sarcoma viral oncogene homologue 2 (active), KRAS, K-ras, K-Ras 2, K-ras p21 protein, KRAS proto-oncogene, GTPase, KRAS1, Kras2, Kras-2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, NS, NS3, oncogene KRAS2, p21, p21 protein, p21B, p21ras, PR310 c-K-ras oncogene, RALD, ras, ras p21, RASK, RASK2, ras-like protein, transforming protein p21, Unknown, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, wu:fa04e08, wu:fc14b12, wu:fc23g10, wu:fj89d12, xRAS2, zgc:85725
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
16653, 24525, 3845
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- Positive control: Mouse brain tissue lysates, human brain tissue lysate, rat brain tissue lysate, human lung carcinoma tissue
- Predicted band size: 21 kDa Subcellular Location: Cell membrane Cytoplasm
- K-RAS (GTPase KRas) belongs to the Ras oncogene family
- Ras proteins bind GDP/GTP and possess intrinsic GTPase activity
- It plays an important role in the regulation of cell proliferation and has a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes in colorectal cancer cells in a ZNF304-dependent manner
- Mutations in the gene can result in leukemia acute myelogenous, leukemia juvenile myelomonocytic, Noonan Syndrome, gastric cancer, and cardiofaciocutaneous syndrome 2.