Ki-67 Recombinant Mouse Monoclonal Antibody (PD00-10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550630-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550630 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
Ki-67
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
E9PVX6, P46013
Gene Symbols
Mki67
Immunogen
Synthetic peptide within human Ki67 aa 1040-1080/3256.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Clone
PD00-10
Conjugate
Unconjugated
Gene
Mki67
Gene Alias
antigen identified by monoclonal antibody Ki 67, antigen identified by monoclonal antibody Ki-67, Antigen identified by monoclonal antibody Ki-67 homolog, Antigen KI-67, Antigen KI-67 homolog, antigen KI-67, proliferation marker protein Ki-67, antigen KI-67-like, cb31, D630048A14Rik, I79_022666, Ki67, Ki-67, KIA, LOW QUALITY PROTEIN: proliferation marker protein Ki-67, marker of proliferation Ki-67, MIB-, MIB-1, Mki67, PPP1R105, Proliferation marker protein Ki-67, proliferation-related Ki-67 antigen, protein phosphatase 1, regulatory subunit 105, RP11-380J17.2, sb:cb31, si:ch211-250b22.7, unnamed protein product, wu:fa11g09, wu:fb57a07, wu:fi14e05
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
17345, 4288
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- Positive control: Human tonsil tissue, human colon carcinoma tissue, mouse large intestine tissue
- Predicted band size: 359 kDa Subcellular Location: Nucleus, nucleolus
- Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases
- The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus
- Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase
- Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis
- Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms
- In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index
- The correlation between low Ki-67 index and histologically low-grade tumors is strong
- Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.