eIF4E Recombinant Rabbit Monoclonal Antibody (JE60-70), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550717-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550717 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
eIF4E
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P06730, P63073
Gene Symbols
Eif4e
Immunogen
Recombinant protein within Human eIF4E aa 118-217/217.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
JE60-70
Conjugate
Unconjugated
Gene
Eif4e
Gene Alias
AUTS19, CBP, EG668879, EIF4E, EIF-4E, EIF4E1, EIF4EL1, Eif4e-ps, EIF4F, eIF-4F 25 kDa subunit, eukaryotic translation initiation factor 4E, eukaryotic translation initiation factor 4E-like 1, eukaryotic translation initiation factor 4E-like protein, eukaryotic translation initiation factor 4-like protein, If4e, MGC111573, mRNA cap-binding protein, OTTHUMP00000219703, OTTHUMP00000219704, OTTHUMP00000219705, translation initiation factor eIF-4E
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
13684, 1977
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: HL-60 cell lysate, Daudi cell lysate, human testis tissue, human colon carcinoma tissue, human breast carcinoma tissue, mouse hippocampus tissue, mouse brain tissue, SK-Br-3
- Predicted band size: 25 kDa Subcellular Location: Cytoplasm, P-body, Stress granule, Nucleus
- eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export
- All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide)
- EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs
- It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F
- The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis
- The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.