CD127 Recombinant Rabbit Monoclonal Antibody (JE37-10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550739-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550739 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
CD127
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P16871
Gene Symbols
Il7r
Immunogen
Recombinant protein within Human CD127 aa 340-439/459.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
JE37-10
Conjugate
Unconjugated
Gene
Il7r
Gene Alias
CD127, CD127 antigen, CDW127, IL 7 receptor, IL 7R a, IL 7R subunit alpha, IL 7R a, IL 7Ra, IL 7Ra, IL7 receptor, IL-7 receptor alpha chain, IL7 receptor subunit alpha, IL-7 receptor subunit alpha, IL7R, IL-7R, IL7R a, IL7R alpha, IL7R subunit alpha, IL-7R subunit alpha, IL7R a, IL7RA, IL-7RA, IL-7Ralpha, IL-7R-alpha, IL7Ra, ILRA, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, Interleukin7 receptor subunit alpha, interleukin-7 receptor subunit alpha, MGC107557, sCD127, soluble IL 7 receptor, soluble IL 7R
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3575
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: K562 cell lysates, SiHa, human tonsil tissue, K-562
- Predicted band size: 52 kDa Subcellular Location: Cell membrane; Secreted
- CD127 (Interleukin-7, IL-7) is a glycoprotein involved in the regulation of lymphopoiesis
- The response of cells to CD127 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer
- CD127 consists of an alpha chain and a gamma chain
- The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules
- CD127 promotes the proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4+ and CD8+ T cells
- The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor
- Diseases associated with CD127 dysfunction include severe combined immunodeficiency and T cell negative/B cell negative/NK positive severe combined immunodeficiency.