IL23A Recombinant Rabbit Monoclonal Antibody (1F6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549906-Each-of-1 | In Stock | ₹ 37,202.00 |
FEMA549906 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,202.00
GST (18%): ₹ 6,696.36
Total Price: ₹ 43,898.36
Antigen
IL23A
Classification
Recombinant Monoclonal
Concentration
1.55 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
Q9NPF7
Gene Symbols
IL23A
Immunogen
A synthesized peptide derived from human IL23
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Western Blot
Clone
1F6
Conjugate
Unconjugated
Gene
IL23A
Gene Alias
il 23, IL 23 A, IL12B, Il-12b, Il12p40, Il-12p40, il23, IL-23, IL-23 subunit alpha, IL23A, IL-23A, IL-23-A, IL23P19, IL-23p19, ILN, Interleukin, interleukin 12B, interleukin 23 p19 subunit, interleukin 23 subunit alpha, interleukin 23, alpha subunit p19, interleukin-23 subunit alpha, Interleukin-23 subunit p19, interleukin-six, G-CSF related factor, JKA3 induced upon T-cell activation, MGC79388, P19, p40, RP23-388G23.1, SGRF, UNQ2498/PRO5798
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
51561
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- IL-23 is a heterodimeric cytokine composed of the p40 subunit of IL-12 disulfide-linked with a protein p19
- p19, like p35 of IL-12, is biologically inactive by itself
- IL-23 interacts with IL-12Rbeta1 and an additional, novel beta2-like receptor subunit with STAT4 binding domain, termed IL-23R
- IL-23 is secreted by activated mouse and human dendritic cells
- Biological activities of mouse IL-23 are distinct from those of mouse IL-12
- Mouse IL-23 was found not to induce significant amounts of IFN-γ
- Mouse IL-23 does induce strong proliferation of memory T cells (but not naive T cells), whereas IL-12 has no effect on memory cells
- Additionally, mouse IL-23 (but not IL-12) can activate mouse memory T cells to produce the proinflammatory cytokine IL-17
- Human IL-23 has biological properties which are less distinct from human IL-12; human IL-23 induces proliferation of memory T cells and induces moderate levels of IFN-γ production by naive and memory T cells, as compared to IL-12.