FEMA550748

Kir2.1 (KCNJ2) Recombinant Rabbit Monoclonal Antibody (JE54-56), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550748-Each-of-1 In Stock ₹ 42,275.00

FEMA550748 - Each of 1

₹ 42,275.00

In Stock

Quantity

1

Base Price: ₹ 42,275.00

GST (18%): ₹ 7,609.50

Total Price: ₹ 49,884.50

Antigen

Kir2.1 (KCNJ2)

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 1% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P35561, P63252, Q64273

Gene Symbols

Kcnj2

Immunogen

Synthetic peptide within Human Kir2.1 aa 91-140/427.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

JE54-56

Conjugate

Unconjugated

Gene

Kcnj2

Gene Alias

ATFB9, cardiac inward rectifier KIR2.1, cardiac inward rectifier potassium channel, EGK_08925, HHBIRK1, HHIRK 1, HHIRK1, HIRK 1, hIRK1, Inward rectifier K, inward rectifier K(+) channel Kir2.1, inward rectifier K+ channel KIR2.1, inward rectifier potassium channel, inward rectifier potassium channel 2, inwardly rectifying potassium channel Kir2.1, IRK 1, IRK1, IRK-1, IRK2, Kcnf1, KCNJ2, KIR2.1, LQT 7, LQT7, Potassium channel, inwardly rectifying subfamily J member 2, potassium channel, inwardly rectifying subfamily J, member 2, potassium inwardly rectifying channel subfamily J member 2, potassium inwardly-rectifying channel, subfamily J, member 2, potassium voltage-gated channel subfamily J member 2, RBL-IRK1, SQT 3, SQT3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16518, 29712, 3759

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Positive control: N2A, SW620, rat uterus tissue, human placenta tissue, mouse brain tissue
  • Predicted band size: 48 kDa Subcellular Location: Membrane
  • The KIR2 subunit family includes 2
  • 1, 2
  • 2, 2
  • 3 and 2
  • 4
  • Unlike G protein-coupled KIR3 subunits, KIR2
  • 1 requires both phosphorylation by PKA and ATP hydrolysis for functional activity
  • KIR2
  • 1 is expressed in the superior and inferior collicula and the pontine region of the brain, where it moderates synaptic transmission, like many other potassium channels
  • In the placenta, KIR2
  • 1 is expressed throughout gestation in cytotrophoblast cells
  • In the kidney, KIR2
  • 1 colocalizes with KIR5
  • 1 in the proximal tubule
  • KIR2
  • 1, 2
  • 2 and 2
  • 3 associate with the membrane-associated guanylate kinase synapseassociated protein 97 in the cerebellum and heart
  • Phosphorylation of KIR2
  • 2 by protein kinase A inhibits the associates with SAP97.