FEMA550752

AFP Recombinant Rabbit Monoclonal Antibody (PD00-71), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550752-Each-of-1 In Stock ₹ 42,275.00

FEMA550752 - Each of 1

₹ 42,275.00

In Stock

Quantity

1

Base Price: ₹ 42,275.00

GST (18%): ₹ 7,609.50

Total Price: ₹ 49,884.50

Antigen

AFP

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P02771

Gene Symbols

AFP

Immunogen

Recombinant full length protein corresponding to Human alpha 1 Fetoprotein aa 1-609/609.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

PD00-71

Conjugate

Unconjugated

Gene

AFP

Gene Alias

a fetoglobulin, a fetoprotein, Afp, AFPD, Alpha fetoglobulin, alpha fetoprotein, alpha-1-fetoprotein, Alpha-fetoglobulin, alpha-fetoprotein, alpha-fetoprotein precursor, alpha-foetoprotein, chloride intracellular channel 6, FETA, fetoglobulin, fetoprotein, HPAFP, a fetoglobulin, a fetoprotein

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

174

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Positive control: Human liver carcinoma tissue, human placenta tissue
  • Predicted band size: 68 kDa Subcellular Location: Secreted
  • AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life
  • AFP expression in adults is often associated with hepatoma or teratoma
  • However, hereditary persistence of AFP may also be found in individuals with no obvious pathology
  • The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4
  • AFP is found in monomeric, dimeric, and trimeric forms
  • AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin
  • The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly
  • High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.